Host microbiomes

Microbial communities associated with hosts play a crucial role in maintaining the health and resilience of organisms, from plants to humans. These host-associated microbiomes influence growth, disease resistance, and the ability to cope with environmental stress. At the ME2andA, our research focuses on uncovering the common mechanisms by which microbes interact with each other and their hosts, especially under stressed conditions. By identifying these commonalities, we aim to develop strategies to enhance host resilience across different systems.

Plant microbiomes

Plants rely on their associated microbial communities for nutrient acquisition, growth, and defense against pathogens. The plant microbiome plays a vital role in helping plants adapt to changing environmental conditions, such as drought or disease pressure. Our research focuses on different plant systems, aiming to unravel how beneficial microbes support plant health and productivity. In addition, we are interested in understanding the evolutionary relationships between plants and their microbiomes in the context of plant domestication and breeding. Ultimately, our goal is to develop microbiome-assisted plant breeding programs that harness beneficial microbes to improve crop resilience and sustainability.

Ongoing research:

1. Bean microbiome

2. Tomato microbiome

3. Wheat microbiome

Human microbiomes

The human microbiome is a complex and dynamic ecosystem that significantly impacts overall health. Microbes help protect against infections, aid in digestion and modulate the immune system. Our research aims to explore how beneficial microbes interact under normal and stressed conditions, and how these interactions can be leveraged to maintain or restore health. By identifying the common triggers that influence these microbial dynamics, we hope to find ways to promote human well-being in the face of environmental or physiological stressors.

Ongoing research:

1. Prophages in prevalent members of the gut microbiome

2. The skin microbiome's role in Staphylococcus aureus prevention